%--------------------------------------------------------------------------- % [Simulation Environment] %--------------------------------------------------------------------------- fnRR = outrr1.txt // output RR interval filename fnAA = outaa1.txt // output AA interval filename fnAV = outav1.txt // output AVJ status filename fnLOG = outlog1.txt // output event log filename MAX_RR = 500 // max RR intervals to run MAX_TIME(s) = 1000.0 // max running time in seconds Ts(s) = 0.001 // sampling interval RR0(s) = 1.000 // initial RR interval %--------------------------------------------------------------------------- % [Atrium Model] %--------------------------------------------------------------------------- AA_MODEL = 0 // AA interval generator method lambda(1/s) = 5 // mean rate of Afib bombardment on AV junction AAstd(s) = 0.0 // standard deviation of AA interval dVmean(mV) = 15 // mean potential increment (dV) by AF bombardment dVstd(mV) = 0 // standard deviation of dV AtrDly(ms) = 0.03 // atr conduction delay from SA node to AVJ S1S2(s) = 0.2 // S1S2 interval of atrial pacing protocol S2S3(s) = 0.5 // S2S3 interval of atrial pacing protocol % AA model: 0-exponential, 1-inv poisson, 2-uniform, 3-Gaussion, % 4-S1S2 pacing, 5-S1S2/S2S3 pacing, 6-fixed %--------------------------------------------------------------------------- % [AVJ Model] %--------------------------------------------------------------------------- Vt(mV) = -40 // AV junction threshold potential Vr(mV) = -90 // AV junction resting potential dVdt(mV/s) = 50 // original V4 (AVJ spontaneous depolarization slope) MinAVDa(s) = 0.070 // minimum anterograde AV conduction delay MinAVDr(s) = 0.070 // minimum retrograde AV conduction delay alpha(s) = 0.130 // max extension of the AV conduction time tau_c(s) = 0.100 // time constant for AV conduction curve MinRef(s) = 0.050 // minimum AVJ refractory period beta(s) = 0.250 // max extension of the AVJ refractory period tau_r(s) = 0.500 // time constant for AVJ recovery curve Ref_std(s) = 0.000 // standard deviation of AVJ refractory period delta = 10 // electrotonic modulation control (strength) theta = 10 // electrotonic modulation control (time) %--------------------------------------------------------------------------- % [Ventricle Model] %--------------------------------------------------------------------------- AntDly(s) = 0.050 // ante conduction delay from AVJ to RV electrode RetDly(s) = 0.150 // retr conduction delay from RV electrode to AVJ ref(s) = 0.100 // ventricular refractory period %--------------------------------------------------------------------------- % [RV Electrode Model] %--------------------------------------------------------------------------- VP_MODEL = 0 // ventricular pacing method BI(s) = 0.80 // standby ventricular pacing basic interval % VP_MODEL: 0-VVI, 1-adaptive VRS, 2-wittkampf, >2(default): VVI