Software Open Access

Generalized Multiscale Entropy Analysis

Published: Feb. 2, 2019. Version: 1.0.0


Please include the standard citation for PhysioNet:

Goldberger AL, Amaral LAN, Glass L, Hausdorff JM, Ivanov PCh, Mark RG, Mietus JE, Moody GB, Peng C-K, Stanley HE. PhysioBank, PhysioToolkit, and PhysioNet: Components of a New Research Resource for Complex Physiologic Signals (2003). Circulation. 101(23):e215-e220.

The method of generalized multiscale entropy (GMSE) analysis is useful for investigating complexity in physiologic signals and other series that have correlations at multiple (time) scales. It represents a generalization of the original method of multiscale entropy analysis.

A tutorial about generalized multiscale entropy analysis is available in the tutorial directory. It discusses various methods for calculating a coarse-grained time series, and the impact of this choice on the multiscale entropy calculation. The results are illustrated using simulated data as well as real inter-beat interval data.

The software described in the tutorial in is gmse.c.


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